AFP-CHECK-1 Quantitative determination of alpha-Fetoprotein in whole blood, plasma or serum samples FOR EASY READER® OR EASY READER+®

Alpha-fetoprotein (AFP) is a single-chain glycoprotein with a molecular weight of approximately 70,000 (1). It is produced by the fetal yolk sac and proximal structures of the liver and gastrointestinal tract. In the human fetus, AFP is a major serum protein which reaches a level of several milligrams per milliliter at week 12 of gestation and then drops to trace concentration in normal non pregnant adult. The clinical value of AFP as a tumor marker was not immediately appreciated because the assays used for quantitation were not sensitive enough to detect the nanogram amounts associated with early disease. As more sensitive radioimmune assays became available, the utility of AFP as a tumor marker became increasingly apparent.

Each kit contains

1. AFP- CHECK-1 reaction devices: 10 20
2. Disposable plastic pipettes: 10 20
3. Diluent in a dropper bottle: 2.5mL 5mL
4. Instruction leaflet: 1 1
5. Controls (Optional): Positive control ref. V8000 and Negative control ref. V8001: a freeze-dried preparation of a non-infectious compound in diluted human serum, tested and found negative for anti-HIV, anti-HCV and HBs antigen, containing 0.05 % sodium azide is optionally available as a positive and negative control (1x 0.25 mL). The concentration range is indicated on the vial label.