CRP-CHECK-1 (Laboratories) Quantitative determination of C-Reactive Protein in whole blood, plasma or serum samples

C-Reactive Protein (CRP) is a non specific, acute-phase reactant used to diagnose bacterial infectious disease and inflammatory disorders, such as acute rheumatic fever and rheumatoid arthritis (1, 2). CRP levels do not consistently rise with viral infections. CRP is an abnormal protein produced primarily by the liver during an acute inflammatory process (3). A positive test result indicates the presence, but not the cause, of an acute inflammatory reaction (4). The synthesis of CRP is initiated by antigen-immune complexes, bacteria, fungi, and trauma. The CRP test is a more sensitive and rapidly responding indicator than the erythrocyte sedimentation rate (5, 6). This test is also useful in evaluating patients with an acute myocardial infarction. The level of CRP correlates with peak levels of the MB isoenzyme of creatine kinase, but CRP peaks occur 1 to 3 days later. Failure of CRP to normalise may indicate ongoing damage to the heart tissue. Levels are not elevated in patients with angina. CRP is classically measured using latex agglutination and nephelometric or turbidimetric methods. CRP-CHECK-1 is a rapid quantitative screening test for the detection of CRP in serum, plasma or whole blood samples. Depending on the CRP concentration, different lines will appear in the reading window, allowing the quantitative measurements of CRP in serum, plasma or whole blood samples, when used in combination with the Easy Reader® or Easy Reader+® rapid test readers.

Each kit contains

1. CRP-CHECK-1 test devices: 10 20
2. Disposable plastic pipettes : 10 20
3. Diluent bottle: 7.5mL 15mL
4. Instruction leaflet: 1 1
5. Controls (Optional): Positive control (ref. V340) and Negative control (ref. V341): a freeze-dried preparation of a non-infectious compound in diluted human serum, tested and found negative for anti-HIV, anti-HCV and HBs antigen, containing 0.05 % sodium azide is optionally available as a positive and negative control (1x 0.25 mL). The concentration range is indicated on the vial label.